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Corporate AlliancesIngenza has entered into a number of relationships with partners for
the industrial implementation of the amine and amino acid deracemisation
technology. These relationships are focused on specific molecules of
interest to the customer and are aimed at tailoring the platform deracemisation
technology (including optimising enzyme specificity through directed
evolution and bioprocess optimisation) towards these specific molecules.
Some of the companies that Ingenza has entered into alliances with to
date are:
In addition to alliances with customers regarding the deracemisation technology, Ingenza has also entered into a number of agreements for the delivery of improved and novel bioprocesses using our general expertise in biocatalysis research. Some of these alliances are shown below.
zuChem is a biotechnology company focused on the development and commercialization of novel, proprietary manufacturing methods to produce glycochemicals (unique sugar-like compounds). While the greatest long term need for such glycochemical companies is by the pharmaceutical industry, the company is, in addition exploiting the significant commercial opportunities for these compounds in the food ingredients, nutraceuticals and flavours and fragrances markets in order to generate near term revenues. The company recently had the first close of its Series A financing round, and is seeking additional capital and strategic partners. For more information on zuChem visit their website at www.zuchem.com Ian Shott Development Ltd.(formerly Great Lakes Fine Chemicals, Holywell, UK)Ingenza entered into a long-term interaction with Great Lakes Fine Chemicals (Holywell Facility), which was recently acquired by Ian Shott Development Ltd., to provide bioprocess improvements to complement existing expertise in unnatural amino acid manufacture. This relationship is delivering specific improvements to existing bioprocesses to further enhance operating efficiency. Research Funding
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Scottish Executive - SMART:SCOTLAND Award |
In May 2003, Ingenza began a one-year research award to develop amine racemase biocatalysts for use in dynamic kinetic resolutions and chiral separations. This prestigious award has allowed Ingenza to develop a new technology platform for the preparation of enantiopure amines.
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European Union - Framework 6 DATAGENOM Project |
This collaborative grant has been awarded to develop a range of biocatalysts and bioprocesses with groups from industry and academia. The aim of the project is to datamine genomes for methods to synthesise novel pharamceutical chiral intermediates followed by the practical implementation of these novel bioprocesses. The other members of the consortium are Prokaria Ltd. (Iceland, www.prokaria.com), Dr. Olle Holst, Lunds Universitet (Sweden), Prof. Dr. Peter Schönheit, Christian-Albrechts-Universität (KIEL, Germany), Prof. Vicente Gotor, University of Oviedo (Spain), Prof. Ralf Mattes, Universität Stuttgart (Germany), Prof. Roger A. Sheldon, Delft University of Technology (Netherlands), Degussa AG (Germany, www.degussa.com) and the BioInfoBank Institute (Poland, www.bioinfo.pl).
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Biotechnology and Biological Sciences Research Council - Small Business Research Initiative |
This prestigious and highly competitive grant has been awarded to Ingenza to fund significant developments within the deracemisation technology platform. The award has allowed Ingenza to expand its research team to focus effort on the diversification of the toolbox of oxidase enzymes that are available for the deracemisation platform, leading to a wider variety of molecules that are applicable to the technology. In addition, the award will provide increased process development resources, leading to faster implementation of the process for a number of molecule classes at larger scale.
copyright 2004
