Success story
Superior enzyme productivity and purity
Customer challenge
High cost of enzyme required for pharmaceutical manufacture, due to poor yield from E. coli and complex purification to remove host endotoxin contamination.
Ingenza’s inGenius® solution
Alternative, GRAS, endotoxin-free B. subtilis production host, employing codABLE™ gene design to optimise productivity of the customer’s biocatalyst.
5x
5x gain in biocatalyst activity.
100%
100% removal of endotoxin contamination.
Delivered
A cost-effective, scalable biomanufacturing process for the target, free of endotoxin. Gene design empowered by machine-learning outperforming leading DNA providers. Optimal production of candidate in soluble form. Strain and process technology transfer package.