Biomanufacturing uses biological systems to produce commercially relevant molecules– such as peptides, proteins, antibodies and small molecules – at scale. Choosing the ideal host organism is crucial for an efficient and economical bioprocess, and mammalian cell lines and Escherichia coli are currently the top choices for biopharmaceutical applications. In this white paper, we discuss the many benefits of choosing an alternative microbial host for the recombinant expression of bioactive molecules, including medicines, vaccines and industrial enzymes. We also outline the specific advantages of Ingenza’s engineered Pichia pastoris yeast strains for GMP-compliant pharmaceutical manufacturing.
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